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- Does orlistat cause acute kidney injury?
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Does orlistat cause acute kidney injury?
Ther Adv Drug Saf. Michael M. BeyeaAmit X. Gargand Matthew A. Author information Copyright and License information Disclaimer. Corresponding author. Matthew A. Amit X. This article has been cited by other articles in PMC. Abstract Orlistat is an inhibitor of gastric and pancreatic lipase with proven efficacy in the augmentation and maintenance of weight loss. Keywords: acute kidney https://hybris.15kilosmenos.site/pagina21943-adelgazar-10-kilos-antes-y-despues-de-cirugias.php, orlistat.
Introduction Obesity is fast becoming a worldwide epidemic. Orlistat efficacy Orlistat, also known as tetrahydrolipstatin is a potent, selective and reversible inhibitor of gastric and pancreatic lipases [ Guerciolini, ]. Proposed mechanism of orlistat-associated AKI Orlistat is thought to cause AKI through enteric hyperoxaluria, which can also be seen in patients with fat-malabsorption syndromes.
Epidemiology of orlistat-associated AKI Although the current literature draws associations between What damage does diet pills do to your body and AKI, it provides little insight into the frequency with which AKI occurs or the factors that may predict it.
Causality Despite the associations between orlistat and AKI, establishing causality between drug exposure and adverse outcome is challenging [ Macedo et al. Conclusion Establishing unequivocal causality in the setting of adverse drug reactions is very difficult.
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